NFC West Odds, Predictions, Betting Picks 2025/26: Seahawks Regained the Division Lead

• Seattle Seahawks regained the division lead (6-2) from the Los Angeles Rams (6-2) due to a tiebreaker (better division record)

• The Los Angeles Rams (6-2) slipped to second place but remain tied for the best record in the division

• The San Francisco 49ers (6-3) are a close third and are positioned as a strong NFC Wild Card contender

NFC West Winner Odds

Odds provided by FanDuel Sportsbook. Place your bets at FanDuel today and claim your bonus: Bet $5, Get $150 in Bonus Bets if Your Bet Wins.

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NFC West Winner - My Pick

San Francisco 49ers (+330) at FanDuel Sportsbook

The San Francisco 49ers are a strong NFC West betting candidate due to their elite, star-studded roster, featuring a top-tier defense (Nick Bosa, Fred Warner) and a dynamic, explosive offense led by Christian McCaffrey. Their proven coaching staff and historical division dominance provide a high floor and ceiling, making them the consistent favorite to secure the division title.

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How to Bet on the NFC West Winner

When betting on a team to win their division, it’s important to factor in their continuity on both sides of the ball. A team who brings in a majority of their players are in a great position to succeed as it helps limit the amount of variance in their contests. Signing productive players throughout the offseason is also vital as it gives you the depth needed to deal with injuries that are sustained during the year to help remain competitive for the duration of the season.

A team’s strength of schedule and situational sports are also very important to consider as an easier schedule drastically increases a team’s chances of finishing in first in their respective division standings. Look to back a team who receives plenty of rest between primetime games and international travel as it reduces the chances of them suffering a devastating injury.

How to Read NFC West Winner Odds

Before placing a wager on a team to win the NFC West, it’s vital to know how the listed odds work. If you bet on the San Francisco 49ers to win the division at their preseason odds of +175, then a $100 wager would profit you $175 if they win the NFC West.

If you wait to see if they get off to a hot start and are listed with a minus sign in front of their odds (-125 for example), then you would need to wager $125 to profit $100. Make sure you line shop before placing a wager as the odds for the same market can vary between each sportsbook.

Where to Bet on the NFC West Winner

FanDuel Sportsbook is one of the top choices to use for the NFL as they consistently roll out amazing promotions for their users to use and are quick to update their odds throughout the season. If you have not signed up yet with FanDuel Sportsbook and are looking to get in on the action, you can claim the following offer: Bet $5, Get $150 in Bonus Bets if Your Bet Wins.

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NFC West Winner History

After dominating the NFC West early in its inception, the San Francisco 49ers and Los Angeles Rams are expected to be in a two horse race for the division title this season. Both teams reside at the top in regard to most division titles as the 49ers currently lead the NFC West with 22 championships while the Rams are in second with 15. The Seattle Seahawks meanwhile are in third with nine while the Arizona Cardinals are in last place with three.