NFL Wild Card Weekend Odds: Odds and Betting Lines for Every Game

• The Seahawks are favored to win the Super Bowl

• The Broncos are the top seed in the AFC

• The Steelers have won 23 straight home Monday Night Football games

The NFL playoffs kick off this weekend with the Wild Card round. Six games are occurring over three days, with the action starting on Saturday. 

The Seahawks and Broncos are the top seeds in their respective leagues, but they’re idle this weekend after earning byes. Here, we will discuss the betting lines and odds for Wild Card weekend.

For more info on the league standings, check our latest NFC Championship odds, along with the AFC Championship odds.

NFL Odds for Wild Card Weekend

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Rams vs. Panthers Odds, Saturday, 4:30 PM EST

The Panthers won the NFC South after the Falcons beat the Saints on the final day of the season. Tampa Bay collapsed at the end of the year, clearing the path for the Rams to make the postseason. 

Carolina beat Los Angeles earlier this season as a double-digit underdog. They’re a 10-point underdog once again. 

Even though Carolina has a win over Los Angeles, there isn’t a route to victory for Bryce Young in this game against one of the Super Bowl favorites. 

• Rams: Spread -10.0 (-110) | Moneyline -600

• Panthers: Spread +10.0 (-110) | Moneyline +450

• Total: Over/Under 46.5 (-110/-110)

Find the latest Super Bowl odds and predictions here.

Packers vs. Bears Odds, Saturday, 8:00 PM EST

The Packers are limping into the playoffs. Jordan Love isn’t healthy, and the team lost Micah Parsons for the whole year one month ago. 

The Chicago Bears are coming off a loss to the Lions, but they still hold the No. 2 seed in the NFC. Ben Johnson has fixed the Bears, and they should have a solid playoff performance. 

Caleb Williams looks excellent, and he will be the reason Chicago finds a way to advance to the Divisional Round.

• Packers: Spread +1.0 (-115) | Moneyline -110

• Bears: Spread -1.0 (-105) | Moneyline -110

• Total: Over/Under 46.0 (-110/-110)

Bills vs. Jaguars Odds, Sunday, 1:00 PM EST

The Jaguars have one of the NFL's most successful stories. They started the season slowly, but Trevor Lawrence had a marvelous stretch, leading Jacksonville to the AFC South title. 

The Jaguars had a tough draw, getting the Buffalo Bills in the first round. Josh Allen can take over games, and he has to typically because of his lackluster defense. 

This is a spot where the Bills should win, but it will be close. Allen’s play will be too much for the Jaguars to handle on Sunday.

• Bills: Spread -1.5 (110) | Moneyline -120

• Jaguars: Spread +1.5 (-110) | Moneyline +100

• Total: Over/Under 51.5 (-110/-110)

49ers vs. Eagles Odds, Sunday, 4:30 PM EST

The Eagles are a complete team, and even though they haven’t played their best, they’re still a much better team than the 49ers. San Francisco took the league by storm with their offense in 2025, but they struggled to stop opponents. 

The 49ers don’t match up against any team with a good defense, so Philadelphia should be an overwhelming challenge. If the Eagles can put pressure on Brock Purdy, who gets rid of the ball fast, Philadelphia will roll into the Divisional Round.

• 49ers: Spread +4.5 (-110) | Moneyline +185

• Eagles: Spread -4.5 (110) | Moneyline -225

• Total: Over/Under 45.0 (-110/-110)

Chargers vs. Patriots Odds, Sunday, 8:00 PM EST

The Patriots will finally be tested during the playoffs. The biggest knock on New England this season was that they haven’t played anyone because of their easy schedule. 

While this is true, the Patriots have beaten most teams badly. Los Angeles isn’t healthy on the offensive line, so New England’s pass rush should feast. 

However, Drake Maye must be better than Justin Herbert. While this is doable, Maye has never played in the playoffs. I’ll still take the Patriots to win a close game.

• Chargers: Spread +3.5 (-110) | Moneyline +170

• Patriots: Spread -3.5 (-110) | Moneyline -205

• Total: Over/Under 46.0 (-110/-110)

Texans vs. Steelers Odds, Monday, 8:00 PM EST

The Steelers have won 23 straight Monday Night Football games at home. They were given this timeslot for the playoffs, which works in their favor. 

However, Pittsburgh will face a challenge from the Texans. Houston has one of the best defenses in the NFL, and they keep quarterbacks contained. 

Aaron Rodgers old age isn’t going to help his cause in this game. The pressure will be too much for Pittsburgh on the line of scrimmage.

• Texans: Spread -3.5 (-105) | Moneyline -185

• Steelers: Spread +3.5 (-115) | Moneyline +155

• Total: Over/Under 39.5 (-110/-110)

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