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Buffalo Bills vs Tennessee Titans Predictions, Odds & Picks

Written by: Mike Lukas
Updated October 14, 2022
12 min read
Bills Vs Titans Week 5
  • The Buffalo Bills QB Josh Allen is proving to be good enough to keep around for awhile
  • The Tennessee Titans’ 3 game winning streak was paused in Week 4 due to COVID-19
  • The last time these two franchises battled each other was last season, Bills 14, Titans 7

Bills vs Titans Odds

Check out our NFL predictions and odds for Week 5 Bills vs Titans game!

Team Point Spread Odds
Buffalo Bills -8.5
Tennessee Titans +8.5


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Bills vs Titans Predictions and Picks

A fully healthy Tennessee Titans would struggle against these Buffalo Bills, but a Titans team that is struggling to field starters might find it next to impossible to beat Josh Allen’s point-scoring Bills.


Bills 8.5 -110

How to Watch Bills vs Titans

Bills vs Titans Information
What Buffalo Bills vs Tennessee Titans
Where Nissan Stadium in Nashville, TN
When Tue, October 13, 2020; 1:00 PM ET
How to watch CBS

The Buffalo Bills are perfect so far, a great deal of that having to do with the success of their young quarterback Josh Allen, who has the team averaging more than 30 points per game with a defense that looks capable (at times) of stopping even the best of teams.

One of the first teams hit hard with the COVID-19 situation was the Tennessee Titans, who suffered an outbreak throughout their organization and had to postpone their Week 4 matchup with the Pittsburgh Steelers, but they remain 3-0 and have one of the best rushing attacks in the league.

These two teams have played each other 47 times (including 3 postseason games), with the Tennessee Titans winning 28 of those games and the Buffalo Bills coming out on top in 19 of the games.

Check out our best NFL week 5 bonuses, here!

Can Bills QB Josh Allen Keep Producing at This Pace?

The Buffalo Bills have their franchise quarterback now, young Josh Allen has been tearing up the league with his gradual adjustment to playing in the NFL.

So far in four games, Allen has completed 105-of-148 for 1,326 total passing yards and 12 touchdowns with just one interception on top of carrying the ball 25 times for 83 yards and 3 touchdowns, the kid being a lot faster and more elusive than he looks.

Allen is a great size – 6’5” and 237 pounds – and he has a cannon for an arm, so if he can continue to develop at this level he can become one of the better athletes at his position in this league.

Can Titans RB Derrick Henry Carry the Team on his Back?

Watch Derrick Henry run with the football – he is patient and then he is powerful, breaking tackles and using his speed to reach the second level, often, typically carrying one or two defenders on his back the entire way.

This season Henry is averaging almost 4 yards per carry on 82 rushes for 319 yards and 2 touchdowns on top of 5 catches for another 26 yards, all this in the three games the Titans have played this season due to postponing their game against the Steelers in Week 3.

The Titans depend on their rushing attack to tire opposing defenses and to keep opposing quarterbacks off the field, so a healthy and productive Henry will be key to their success in Week 5, especially if their main receiving targets can’t play due to their quarantine.

Bills Key Player: (RB) Devin Singletary

In Week 4 in their tight win against the Los Angeles Rams, Bill RB Devin Singletary had 13 carries for 71 yards, averaging 5.5 yards per carry and giving the team a respectable run threat to which defenses must pay attention.

He also has soft hands, with 16 catches off 21 targets in 2020 for a total of 114 yards but no touchdowns, a dual-threat out of the backfield that forces opposing teams to game plan around his potential production.

For the Bills to do well and outscore this Titans team, they will have to edge them out in ball possession and there is no better back to help get that done than Singletary, who has 50 total carries so far on the season.

Editor’s Picks

Titans Key Player: (WR) Kalif Raymond

Titans receiver Kalif Raymond put on a show in Week 3 during the Titans win over the Minnesota Vikings, posting 3 receptions for 118 yards, averaging almost 40 yards per catch.

In the first two games of the season, Raymond had no catches off two targets, so the fact that he proved he can be productive in Week 3 should give QB Ryan Tannehill another reliable receiver to target besides AJ Brown.

Raymond is also valuable as a kick and punt returner, so far with a kickoff return of 30 yards and two punt returns for a total of five yards.

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Mike Lukas

1204 Articles

Mike Lukas is a retired standup comedian turned freelance writer now living in Dallas, Texas, originally from Cleveland, Ohio. His love for the game of football and all things Cleveland Browns turned Mike into a pro blogger years ago. Now Mike enjoys writing about all thirty-two NFL teams, hoping to help football gamblers gain a slight edge in their pursuit of the perfect wager. Email: [email protected]

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