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The Arizona Cardinals don’t just have one of the most recognizable logos in the league, but they are actually the oldest team in the NFL. Dating back to 1898 as the Chicago Morgan Athletic Club, the Cardinals would soon rename and relocate a few times before finding a forever home in the Copper State in 1987. 

Unfortunately, the Cardinals haven’t had a productive season since 2021, but who’s to say that this year will be the same, and they might be a good team to keep an eye on when placing bets at some of your favorite sportsbooks.

This team guide will detail everything you need to know about the Arizona Cardinals for this upcoming season, in hopes of you getting some returns on your wagers on The Cards in 2025-2026.

Arizona Cardinals Odds NFL Regular Season 2025/2026

Below are the odds being provided by FanDuel Sportsbook, one of the nation’s best sports betting sites. If you want to find out more about this platform, read our FanDuel Sportsbook review, which will tell you all you need to know before placing any bets of your own.

Arizona Cardinals Odds Regular Season Win Totals

WinsOdds
Over 5.5 Wins-650
BET HERE
Under 5.5 Wins+490
BET HERE
Over 6.5 Wins-290
BET HERE
Under 6.5 Wins+240
BET HERE
Over 7.5 Wins-140
BET HERE
Under 7.5 Wins+120
BET HERE

Arizona Cardinals Futures Odds

WinsOdds
NFC Championship Winner 2025-26+4500
BET HERE
Super Bowl LX Winner+10000
BET HERE
Kyler Murray to win AP NFL Regular Season MVP 2025-2026+20000
BET HERE

Find more Futures markets to bet on this season, use our predictions, and the latest NFL Futures odds.

Team Odds and Betting Markets 

Here are some of the most popular types of bets you will find at sportsbooks, and what betting $10 on hypothetical Cardinals games would result in.

Team Point Spread

A point spread is used to make a game “even”, especially when there is a clear favorite to win. The clear favorite must win by more than the spread for the wager to be successful, and if the underdog loses by less than the spread (or wins), the bet is still covered. Usually, both sides of the bet will pay out the same.

Let’s see a hypothetical game between the Cardinals and 49ers to see how a team point spread works with a $10 bet and -110 odds:

  • Spread: Cardinals +7 vs. 49ers -7 (Cardinals are the underdogs and 49ers the favorite)

  • Cardinals win by more than 7: Your wager is successful

  • Cardinals lose by less than 7: Your wager is successful

  • Cardinals lose by exactly 7: Bet is a push, and you get your money back

  • Cardinals lose by more than 7: You lose the bet

With -110 odds, you would win $9.09 in profit and get a net return of $19.09.

Team Over/Under

With an over/under bet, you are not betting on a team to win, but you are instead betting on the total score of the game. The sportsbook will set a number, referred to as the “line”, and you have the option to choose whether the score will be over or under it:

  • Over: Total score will be more than the line

  • Under: Total score will be less than the line

Here’s how an over/under of 44.5 points with the Cardinals vs. Rams:

$10 wager at -120 odds on over 44.5 points:

  • Total score is over 44.5 points: Bet wins

  • Total score is under 44.5 points: Bet loses

  • As it’s 44.5, a push is impossible

  • Win: Profit equals $8.33 on your wager

$10 wager at +100 odds on under 44.5 points:

  • Total score is under 44.5 points: Bet wins

  • Total score is over 44.5 points: Bet loses

  • Push is impossible 

  • Win: Profit equals $10.00 on your bet

Team Moneyline

Team moneylines are the most straightforward bet, as you are betting on which team you think will win the game. When betting on the favorite to win, you will see less money won in profit, as bookies are expecting that team to walk away victorious. If you bet on the underdog and they win, you will see a greater return.

Let’s look at a hypothetical team moneyline bet:

  • Cardinals: +200 (underdog)

  • Seahawks: -250 (favorite)

If a $10 bet on the Cardinals to win were placed, with +200 odds, it would result in a $20 profit and a total return of $30. However, if a wager was placed on the Seahawks to win with -250 odds, the profit would only be $4, as they were the favorites, and a total return of $14 would be made.

Team Props

A prop bet is a wager relating to a specific statistic in a game, such as the number of tackles, touchdowns, yards, etc. However, a team prop bet relates to a single team’s performance during a game, such as the number of team touchdowns, team tackles, or yards, for example. The odds will vary on team prop bets as they are a bit more specialized.

Here is how a team prop bet would work on the number of touchdowns scored in a game:

$10 bet on over 2.5 TDs at +150 odds:

  • Cardinals score more than 2.5 TDs: $15 profit made

  • Cardinals score less than 2.5 TDs: Bet lost

$10 bet on under 2.5 TDs at -180 odds: 

  • Cardinals score less than 2.5 TDs: $5.55 profit made

  • Cardinals score more than 2.5 TDs: Bet lost

Team Futures

A futures bet is making a bet on something that will happen later in the season, for example, placing a bet on the Cardinals to win the Super Bowl, making the playoffs, or winning their division. These wagers are a lot harder to predict, so the odds will be a lot larger than the game-by-game bets that are, in theory, easier to predict. 

If you stuck a $10 bet on the Cardinals to win the NFC West with odds of +5000, you would see a profit of $500. Whereas if you put the same bet on the Chiefs to win the AFC West at -300 odds, which is a lot more likely to happen, your profit would only be $3.33.

If you want to find out more about betting on the NFL, check out the resources we have available at WSN.

Team Schedule 

WeekDateOpponent
Week 1Sun, 09/07, 10:00 AM MST@Saints
Week 2Sun, 09/14, 1:05 PM MSTPanthers
Week 3Sun, 09/21, 1:25 PM MST@49ers
Week 4Thu, 09/25, 5:15 PM MSTSeahawks
Week 5Sun, 10/05, 1:05 PM MSTTitans
Week 6Sun, 10/12, 10:00 AM MST@Colts
Week 7Sun, 10/19, 1:25 PM MSTPackers
Week 8 (Bye Week)N/AN/A
Week 9Mon, 11/03, 6:15 PM MST@Cowboys
Week 10Sun, 11/09, 2:15 PM MST@Seahawks
Week 11Sun, 11/16, 2:05 PM MST49ers
Week 12Sun, 11/23, 2:05 PM MSTJaguars
Week 13Sun, 11/30, 11:00 AM MST@Buccaneers
Week 14Sun, 12/07, 2:25 PM MSTRams
Week 15Sun, 12/14, 11:00 AM MST@Texans
Week 16Sun, 12/21, 2:05 PM MSTFalcons
Week 17Sat, 12/27, TBD@Bengals
Week 18Sun, 01/04, TBD@Rams

Arizona Cardinals Team History

Arizona Cardinals Odds Jalen Thompson

The Arizona Cardinals played their first game in the NFL in 1920 as the Chicago Cardinals and they’re one of only two of the NFL’s original charter members that are still playing today, the other being the Chicago Bears. But the Cardinals’ history actually started more than two decades before in 1898 as an amateur team called the Morgan Athletic Club.

The Cardinals won two league championships in 1925 and 1947 but have not won a Super Bowl in the Modern era. In 1960 the team moved to St. Louis and moved to Phoenix, Arizona in 1988.

The Cardinals’ lone NFC Championship victory was in 2008 but they lost in the Super Bowl against the Pittsburgh Steelers, three NFC West division titles, and 11 playoff appearances. They played the Pittsburgh Steelers in Super Bowl XLIII, losing 27-23 after giving up a late touchdown to WR Santonio Holmes.

The Cardinals have never had a true franchise quarterback, although that may soon change recently with the drafting of Kyler Murray. Some of the organization’s biggest names include Larry Fitzgerald, Kurt Warner, and Jim Hart. 

The Cardinals currently hold a 135-167-2 record since joining the NFC West. Keep track of how they're doing in the NFC West right here:

NFC West Odds for the Cardinals

Start Betting on the Arizona Cardinals

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Arizona Cardinals FAQ

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Jasper Bushby-Edwards

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