wsn-newsletter

NFL Odds Week 8: Odds and Betting Lines for Every Game

Published: October 21, 2025, 10:00 AM ET
10 min read
  • Lamar Jackson is questionable for Sunday’s game against the Bears

  • The Bills are favored to win the Super Bowl 

  • Six teams are on bye weeks 

Lamar Jackson and the Ravens were supposed to start their comeback tour in Week 8. However, this is on hold as Jackson is still sidelined with an injury and questionable for Sunday’s game against the Bears. 

While the Ravens have consumed the news cycle, there are still many big games to look at in Week 8 as multiple Super Bowl contenders take the field. 

Here, we will give a short analysis of each game on the board with our pick. 

NFL Odds for Week 8

Odds courtesy of bet365 sportsbook. bet365 is one of our favorite NFL betting sites. If you bet $5, you get $200 in bonus bets by using our promo code WSN365 at registration.

Matchup Spread Total Moneyline
Vikings
vs
Chargers
+3.0 (-110) O 44.5 (-110) +135
-3.0 (-110) U 44.5 (-110) -160
Dolphins
vs
Falcons
+7.0 (-110) O 44.5 (-110) +275
-7.0 (-110) U 44.5 (-110) -350
Jets
vs
Bengals
+6.5 (-105) O 44.5 (-110) +245
-6.5 (-115) U 44.5 (-110) -305
Browns
vs
Patriots
+7.0 (-110) O 40.5 (-110) +280
-7.0 (-110) O 40.5 (-110) -360
Giants
vs
Eagles
+7.0 (-110) O 43.5 (-110) +275
-7.0 (-110) U 43.5 (-110) -350
Bills
vs
Panthers
-7.5 (-110) O 45.5 (-110) -425
+7.5 (-110) U 45.5 (-110) +325
Bears
vs
Ravens
+6.5 (-110) O 50.5 (-110) +260
-6.5 (-110) U 50.5 (-110) -320
49ers
vs
Texans
-1.5 (-110) O 41.5 (-110) -125
+1.5 (-110) U 41.5 (-110) +105
Buccaneers
vs
Saints
-5.5 (-110) O 47.5 (-105) -260
+5.5 (-110) U 47.5 (-115) +210
Cowboys
vs
Broncos
+3.0 (+100) O 49.5 (-110) +145
-3.0 (-120) U 49.5 (-110) -170
Titans
vs
Colts
+14.0 (-110) O 47.0 (-110) +650
-14.0 (-110) U 47.0 (-110) -1000
Packers
vs
Steelers
-3.0 (-120) O 45.0 (-110) -185
+3.0 (+100) U 45.0 (-110) +155
Commanders
vs
Chiefs
+10.0 (-110) O 48.5 (-110) +450
-10.0 (-110) U 48.5 (-110) -600

Bet $5 at bet365 and Get $200 in Bonus Bets

Best NFL Sportsbooks
How We Rate
Affiliate Disclaimer
21+
Biggest Payouts
Sleeper # 1
Sleeper star 4.2/5
Sleeper Review
$100 Deposit Match
Claimed 1 time today
Claim Now
21+ Terms and Conditions Apply.
Betr # 2
Betr star 3.8/5
Betr Review
$200 Deposit Match + $10 on Signup
Claim Now
21+ T&Cs Apply
FanDuel # 3
FanDuel star 4.5/5
FanDuel Review
100% Deposit Match up to $100
Claim Now
21+ | Min Deposit $10. T&Cs apply
OwnersBox # 4
OwnersBox star 4.5/5
OwnersBox Review
$100 Deposit Match Bonus
Claim Now
Wanna Parlay # 5
Wanna Parlay star 4.1/5
Wanna Parlay Review
Deposit Match up to $250
Claim Now
Underdog # 6
Underdog star 4/5
Underdog Review
Play $5, Get $100
Claim Now
18+ Terms and Conditions Apply
Playsqor # 7
Playsqor star 4/5
Playsqor Review
100% Deposit Match
Claim Now
Chalkboard # 8
Chalkboard star 4.3/5
Chalkboard Review
Deposit Match up to $100 + a Free Square on First Entry
Claimed 1 time today
Claim Now
No Purchase Necessary. Void where prohibited. All bonus funds returned from free entries require a 1x play-through before withdrawal. Other restrictions apply. Must be 18+ to enter (19+NE, 21+ MA) and present in a state where Chalkboard operates. Concerned with your play? Call 1-800-GAMBLER or visit www.nop.ambling.org
NFL Odds Week 8

Vikings vs. Chargers Odds, Thursday, 8:15 PM EST

The Los Angeles Chargers need to respond following a horrendous performance against the Colts. Los Angeles was defeated 38-24 at home, and were down 23-3 in the third quarter. 

Justin Herbert turned the ball over twice, and the Chargers couldn't find any sustained offensive success early in the game. It will be very hard for Los Angeles to move the ball on the Vikings, who have one of the best defenses in the NFL. 

Minnesota is also coming off a loss to the Eagles. The Vikings aren’t the best team, but they play hard and the Chargers look lost on both sides of the ball. 

Dolphins vs. Falcons Odds, Sunday, 1:00 PM EST

The Miami Dolphins haven’t won a game on the road this season. They’re also on the verge of firing their head coach Mike McDaniel. 

The Dolphins were smoked by the Browns, and the team has seemed to give up on the season. Atlanta is coming off a bad loss to the San Francisco 49ers where they failed to manage the game in critical situations. 

This is a perfect spot for Atlanta to respond, and they should lean on Bijan Robinson throughout the game. 

Jets vs. Bengals Odds, Sunday, 1:00 PM EST

Tyrod Taylor will most likely start for the Jets after Justin Fields got benched last week. Fields was 30th in passing yards and 31st in QBR, so Aaron Glenn had no choice but to bench the quarterback. 

The Jets are 0-7 and have only been on the road twice this season. The Bengals are coming off a fantastic win over the Steelers, who beat New York to open the year. 

Joe Flacco gives Cincinnati a great chance to win and cover after his 342-yard performance last Thursday. 

Browns vs. Patriots Odds, Sunday, 1:00 PM EST

The Cleveland Browns had their best offensive game of the season last week against the Dolphins. Quinshon Judkins scored three touchdowns as Cleveland rolled the Dolphins, 31-6. 

The Browns are 0-3 on the road this season, and they’ll have an extremely tough test against the Patriots. Drake Maye is top five in NFL MVP odds, and New England is first in the AFC East

Maye has thrown for 12 touchdowns and just two interceptions this season. The Patriots' offense will overpower the Browns throughout this game. 

Giants vs. Eagles Odds, Sunday, 1:00 PM EST

The Eagles are leading the NFC East at 5-2. One of their losses came against the Giants in a blowout. 

Even though Philadelphia dropped a game to New York earlier this season, they’re still better in every facet of the game. AJ Brown caught two touchdowns last week, and Philadelphia has seemed to find their passing game. 

If Jalen Hurts can find Brown and DeVonta Smith in the deep passing game, the Giants don’t have a realistic chance. New York will need the Eagles to create self-inflicted wounds to prevail for the second time against Philadelphia. 

Bills vs. Panthers Odds, Sunday, 1:00 PM EST

The Bills lost to the Falcons in prime time in Week 6, and now they’re coming off a bye week. Buffalo with time to prepare, will be hard to beat, especially for an inferior opponent in the Panthers. 

Carolina beat New York last week, but beating the Jets isn’t a very big deal. Buffalo has one of the best quarterbacks in the league with Josh Allen, and they should put up a lot of points off their bye week. 

Allen hasn’t been spectacular this season, but he is a challenge for any defense. 

Bears vs. Ravens Odds, Sunday, 1:00 PM EST

The Baltimore Ravens were expected to win the AFC North this season, but this would be a shocking outcome after seven games. The Ravens are 1-5 on the season, and they’re still without their starting quarterback, Lamar Jackson. 

The odds would suggest that Jackson will play against the Bears, and the team needs him back on the field. The Ravens can only afford to lose three more games to give themselves a chance at the playoffs. 

The Bears present the Ravens with some challenges, but it’s hard not to trust Baltimore coming off a bye week. 

49ers vs. Texans Odds, Sunday, 1:00 PM EST

The San Francisco 49ers beat the Atlanta Falcons in Week 7, and they’ll look to keep their momentum rolling against the Texans. Houston has a fantastic defense, but they’ve struggled to score points. 

CJ Stroud hasn’t done anything special, and he will have to score to keep pace with the 49ers. Christian McCaffrey has been one of the best players in the league this season, and he has kept the team afloat with all their injuries. 

McCaffrey leads the league in carries and has nearly 1,000 all-purpose yards through seven games. Look for San Francisco to lean on their feature back in this contest. 

Buccaneers vs. Saints Odds, Sunday, 4:05 PM EST

The Tampa Bay Buccaneers are leading the NFC South and will face a divisional opponent in the Saints on Sunday. Spencer Rattler is coming off his worst game of the season, where he threw three interceptions. 

The quarterback has been relatively efficient this season outside of this game. He should bounce back, but Tampa Bay is too strong. 

The Buccaneers will be without Mike Evans for the game after his Week 7 injury, but they still hace enough receiving talent to win. 

Cowboys vs. Broncos Odds, Sunday, 4:25 PM EST

The Dallas Cowboys are being carried by the offense. Dak Prescott looks outstanding at quarterback, ranking second in the NFL in passing yards with 1,881. 

He has the best QBR in the NFL, and has a deadly receiver duo on his side with George Pickens and CeeDee Lamb.

The Broncos are coming off a 19-0 fourth-quarter comeback where they scored 33 points in the final 15 minutes. The Broncos' defense and surging offense should be enough to beat Dallas. 

Titans vs. Colts Odds, Sunday, 4:25 PM EST

The Indianapolis Colts hold the top seed in the AFC. Daniel Jones has revived his career in Indianapolis, and this means the Titans won’t have an easy time pulling off a road upset. 

Tennessee is pacing to be the last place team in the AFC South. Cam Ward has potential, but this franchise is in turmoil. 

They just fired their head coach Brian Callahan, and they’re facing the most connected team in the NFL. 

Packers vs. Steelers Odds, Sunday, 8:20 PM EST

Aaron Rodgers will make his return to Green Bay to face the Packers on Sunday Night Football. The Packers are the NFC Championship favorites, and they’re significantly better than Pittsburgh coming into this game. 

The Steelers were defeated by the Bengals in Week 7, and their secondary looked terrible. The Packers have a strong play-action game with Jordan Love, and this should give Pittsburgh headaches on the road. 

Commanders vs. Chiefs Odds, Sunday, 8:20 PM EST

Jayden Daniels suffered an insignificant hamstring injury against the Cowboys in Week 7. His status for Week 8 is unclear, but if he doesn’t play, Washington most likely won’t win.

The Commanders have one of the worst passing defenses in the NFL, and this isn’t a winning formula against the Chiefs. 

Patrick Mahomes has been excellent throwing the ball downfield, and Rashee Rice is back in the lineup for the team, which adds explosiveness to the offense.

Get $200 in Bonus Bets When Betting $5 at bet365

tip_r

Responsible Gambling

If you or someone you know needs support or wants to speak with a professional about responsible gambling, seek out the correct resources. Call or text 1-800-GAMBLER (US), 877-8-HOPENY (NY), 1-800-327-5050 (MA), 1-800-NEXT-STEP (AZ), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR) to get help. Visit 1800gambler.net for more information.

WSN is an advocate for safe gambling practices. Visit our Responsible Gambling Center for more details.

Tanner Kern

Tanner Kern

Sports Betting Analyst & On-Air Host

Expertise:
MLB
NCAAB
NCAAF
NFL
Online Sports Betting
Tanner Kern has been working in the betting industry since 2020. He currently is a social media content creator at DraftKings and contributes to multiple sites in addition to WSN, including Forbes and VSiN. He is also the cohost of the podcast Ride the Line at WSN.
Email: [email protected]
Nationality: American
Education: M.S in Sports Journalism
Favourite Sportsbook: Fanatics Sportsbook
Favourite Casino: Caesars Palace
Experience: 4 years
We've been featured on:
espn logo
reuters logo
cbs-news logo
forbes logo
entrepreneur logo
entrepreneur logo
We only list licensed sportsbooks

We support responsible gambling. Gambling can be addictive, please play responsibly. If you need help, call 1-800-Gambler, players in Washington to contact 1-800-547-6133.

WSN.com is managed by Gentoo Media. Unless declared otherwise, all of the visible content on this site, such as texts and images, including the brand name and logo, belongs to Innovation Labs Limited (a Gentoo Media company) - Company Registration Number C44130, VAT ID: MT18874732, Quad Central, Q4 Level 14, Central Business District, Triq L-Esportaturi, Birkirkara, CBD 1040, Malta.

Advertising Disclosure: WSN.com contains links to partner websites. When a visitor to our website clicks on one of these links and makes a purchase at a partner site, World Sports Network is paid a commission.

Copyright © 2025